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Leading PCR Expertise for the Automated Workflow
The automated thermal cycler Biometra TRobot II allows a high-throughput PCR workflow with 24/7 reliable, unattended operation with highest quality of results for routine PCR or incubation applications. It is ideal for molecular biology labs that face a large number of samples every day and need to rely on the analysis results of their valuable samples.
In addition to the typical main application, the polymerase chain reaction (PCR), the Biometra TRobot II is also suitable for all other molecular biological or chemical incubations in PCR plates. For example, the generation of libraries for Next Generation Sequencing (NGS) is an important step in a larger workflow where the automated thermal cycler can be used. This reduces the manual effort and the possibility of errors. The PCR cycler has outstanding heating and cooling rates and excellent temperature homogeneity across the sample block for highly reproducible PCR results. For the setup of new protocols or for the transfer of existing protocols from other thermal cyclers it is sometimes necessary to make slight optimizations to the protocols. For this purpose the Biometra TRobot II includes a gradient function. With this function it is possible, to test different temperatures in the critical annealing step of the PCR in one run.
In automated systems, compact components with the smallest possible footprint are particularly important. The Biometra TRobot II meets this requirement through its modular design with a compact PCR module that is placed directly on the automation deck, while the controller can be stored underneath the platform. Another important point in automation is that all components should be very robust and reliable. If one component fails, the entire workflow comes to a halt. With this background, we have developed a special, patent-pending mechanism for opening and closing the lid of the Biometra TRobot II, which is intended for permanent use. At the same time, the block design was designed to enable the gripper to access the sample block from three sides. This opens up many possibilities for positioning the thermal cycler on the deck.
A conveniently prepared library allows a fast integration into automation systems. In addition, powerful computer software, the Biometra TSuite, is available for direct control of the automated thermal cycler, which is helpful for first PCR runs in preparation for the actual application. Maximum user safety is ensured with a unique, touch-sensitive safety frame which immediately stops the lid closing in case of contact with a resistance. The smooth block surface without gaps is essential for easy and effective cleaning and decontamination. For stress-free work it is also important to keep the noise level low. The ventilation system has been designed to remain very quiet, even at high performance levels. This allows you to work next to Biometra TRobot II concentrated!
Ensured work success thanks to reproducible, reliable results in high quality
Win walk-away time thanks to the possibility of reliable unattended 24/7 operation
Convenient operation by dedicated software or via complete integration into scheduler software
Minimum downtime thanks to more than 30 years of experience in thermal cycler development and robust equipment design.
Contact us for expert advice for your needs and budget.
Integration software
Sample Block
Block capacity
Proposed sample volume
Maximum Heating
Average Heating
Dimension (width x depth x height)
Maximum Cooling
Average Cooling
Temperature uniformity
Gradient
Max./Min. gradient
Adjustable gradient range
Block exchange
Tempering method
Standby temperature
Temperature control mode
Adjustable temperature range
Temperature control accuracy
Lid type
Space requirement (width x depth x height)
Lid temperature
Contact pressure
Compatible sealing systems
Plate lifter
Consumable compatibility
Time increment
Temperature increment/decrement
Additional dimensions
Required clearance zone
Biometra TRobot II 384 G, 230 V
Biometra TRobot II 96 G, 230 V
Biometra TRobot II 96 SG, 230 V
Biometra TRobot II Controller 230 V
Biometra TRobot II PCR Module 384 G
Biometra TRobot II PCR Module 96 G
Biometra TRobot II PCR Module 96 SG
The unique arc-shaped opening movement has many advantages: In addition to a low instrument height, the sample block is completely accessible for the gripper from three sides. The vertical closing of the lid with software adjustable pressure on the sample plate ensures completely uniform conditions in all sample positions regardless of the height of the plate and sealing material. This feature ensures best reproducibility of results. The particularly robust and patent-pending single-motor mechanism is ideally designed for 24/7 use.
For a workflow without interruptions it is very important that the sample plate can be removed smoothly from the block. Since plates can get stuck on the block after long incubation at different temperatures, the Biometra TRobot II contains a patent-pending system with four small motor-driven plate lifters. When the lid is opened, they gently lift the plate out of the block and are then immediately recessed. This unique system is compatible with all full-skirted plates. A simple adapter frame is available for half-skirted plates.
The Biometra TRobot II is completely controlled by external software – typically integrated into the robot software or via the Biometra TSuite computer software. This software offers a full range of functions for controlling the cycler, creating programs, managing the device and documenting its relevant states and actions in detail. Encrypted data transmission ensures the integrity and security of your data. Various log files enable GMP-compliant use and, in the event of malfunction, help locate the cause of the error prior to a service visit. The number of addressable instruments is almost unlimited – up to 1,000 devices can be managed by the software.